Picarelli played Division I soccer at Pepperdine University and was a three time all-star and the team's top defensive player in 2005. She also holds school records for single season saves (119), career saves (319), goals against average (0.81), goalkeeper wins (45), solo shutouts (32), goalkeeper games played (73) and goalkeeper games started (70).
After her university career, Picarelli played professionally in Italy for ASD CF Bardolino Verona, winning three Italian League Championships and two Italian Cup Championships.
She also played twice in the UEFA Champions League in 2008 and 2009 and was the Italian National Team's starting goalkeeper for the 2009 Eurocup.
